With the SMC near the zenith for about five hours I decided to collect 80 frames for each exposure over some nights.
80 X (15s, 30s, 60s, 120s and 240s) at 300mm at f/3.6 at an ISO of 1600 and fridge at -12C.
Medium image 8MB. FoV is 5.5 X 4.0 degrees.
The image has very good detail and low noise. This excessive data collection would be impractical for mosaics.
It works well for the dim detail in this galaxy. The dust lanes are clearly visible if you look hard.