thanks for the replies, I agree M104 is pretty impressive and handles magnification pretty well, But NGC 5128 is best for me at around 50x - 100x magnification (even then, M104 still takes the lead, I don't know why northern observers complain!

). I must admit, in terms of ease, NGC 5128 is really easy to find for me.
M104 sits in the middle of no where

I havn't tried looking for NGC 253 yet, it's my spring/summer target, so if anyone has seen it, please leave some feedback