As Scott says, the best scope is the one you use the most.
Is portability an issue ? Are you OK at carting it around in and out of doors, down stairs . Do you need to take it with you anywhere for viewing and will it fit in the car?
Things like these over time can get quite laborious. The 12 inch weighs slightly heavier than the 10" , however, its bulk that makes moving it awkard. Having said that, you can knock up some type of trolley to wheel it in/out.
If none of those are concerns, or you think are manageable, go the 12".
One good thing about using avg eyepieces make you really appreciate the premium ones!
Good Luck

Norm