"ms"

[multiweb (Marc)]

Very hard to say as nobody can really know or feel what you and your wife are going through. If it doesn't involve any life threatening procedure and it makes your wife's life any better than what it is now then go for it. At the end of the day you want to make her daily life as good and as comfortable as you possibly can and if there is even the tiniest remote possibility to do it then IMHO it's worth a shot. Ultimately it's her decision. Good luck with it all

[jjjnettie (Jeanette)]

You guys are wonderful.
Do you know that?

[Gallifreyboy]

"My argument here is how hard would it be to set up and run a clinical trial for this comparatively easy procedure

A get 50 MS sufferers

1) test to see if these MS patients have blocked blood vessels in the brain
2) perform procedure on the test group
3) see if any improvement over time 12-18 months
4) get feedback
5) publish results 2 years max "

Originally Posted by dpastern

It wouldn't be hard at all Trevor. But doctors feed the pharmaceutical companies, and they like to make lots of money.
Dave

I shake my head Mr Pastern, if you have something positive to say, go for it, if not you are displaying to the world your ignorance and angst on this issue, why bother

I am a medical researcher but not in neurological conditions. In my time I have seen many major breakthroughs in medical conditions both pharmaceutical sponsored and non-pharmaceutical company sponsored. I work with many researchers whose lives are devoted to discovering better treatments. Mr Pastern's comments are deeply offensive to me.

The difficulties of setting up a human intervention trial in Australia and most first world countries are enormous but not insurmountable. A well thought out scientifically sound and procedurally safe study will get through the many hoops to be registered with the TGA but then the logistics of procedural and study indemnity, having sites with expertise to collect the information and comply with GCP, approval from human research ethics committees etc are difficult. There is often an unrealistic expectation from those who are not involved in human research as to how easy it is to arrange. For those of us who are, patience and diligence (and funding) are the keys. Here is an idea of just 1 general document from TGA about doing trials on unregistered devices http://www.tga.gov.au/docs/html/hrec.htm

For Trevor, don't be discouraged by the hurdles but keep an open mind about the possibilities. Unless a trial is already well advanced in the planning stages in Australia already it will take a long time to get going. You can check if there are similar trials going on currently in Australia by visiting this site http://www.anzctr.org.au/

[dpastern (Dave Pastern)]

Tell me Peter, why does it take a long time to get going? There's enough people. There's enough doctors to do the procedure. So, what's the hold up? These are people's health that you "medical experts" are playing with. You mention hoops. That speaks volumes of the current medical system. Trevor's trying to keep his mind open about possibilities, hence his original post in his thread. When he questioned the possibility of trials in Australia, I showed healthy scepticism, and you've pretty much confirmed it in your most recent post.

I don't really give a hoot what you think of me, or my comments. There is sufficient evidence to show collusion between a lot of doctors and the pharmaceutical companies. Our governments do very little about it for a variety of reasons.

Anyways, my apologies Trevor, but I felt it necessary to react to Peter's comments about me. My suggestion to you Peter - grow a thick skin.

Dave

[TrevorW]

Thanks Peter and David you have both have valid points

but Peter the particular document you refer to relates to therapeutic goods often such things get bogged down in bearacracy to the detrement of those concerned just so people cover thy asses so too speak

If an individual is prepared to sign a waiver and understands that it may not be that magic bullet then so be it

In this case the procedure involves no drug trials

the test for the blood vessel blockage is quite common I think it's referred to as a Doppler

likewise the procedure to clear blood vessels of blockage is quite common

so I cannot see why there should be prolonged delays in setting up clinical trails on a group of test subjects

sorry it may seem cynical but it just doesn't make sense.

[marki]

Trevor you best contact the Dr directly. I know plenty of people who have gone OS to get treatment when the option is not available here. The Italians do great things with bone damage and are quite innovative in their approach to many things medical. If the scan can be done here on request of a GP to find out if the treatment is suitable then that would be the best way to go about it. Won't be cheap but what price for the health of a loved one.....

Mark

[dugnsuz (Doug)]

Dr Zamboni's surgical procedure seems like a real step forward for sufferers of MS (and their carers) much in the tradition of medical pioneers who go out on a limb to test their own theoretical ideas like Barry Marshall with Helicobacter Pylori.
I wish you and your wife all the best in pursuing this treatment - this is very new, non clinically trialed medicine and as such requires the patient to have the financial and motivational wherewith-all to actively pursue it.
I hope you can.
All the best
Doug

[Jen]

Hey Trevor
I hope things turn out ok for you and your wife go for it i say if thats what your wife wants to do, in the end it will be her decision to make.
And you also need to take care of yourself too ok, you sound like a very lovely supporting husband
All the best Trev
xo

[slippo74 (Cristiano)]

Hi Trevor, I wish all the best for your wife.
If you are planning to go in Italy, I just want to let you know that I still have my house over there and you are more than welcome to use... I believe it may help in some way in case you need to stay for a long period.

Cheers.

[TrevorW]

Originally Posted by slippo74

Hi Trevor, I wish all the best for your wife.
If you are planning to go in Italy, I just want to let you know that I still have my house over there and you are more than welcome to use... I believe it may help in some way in case you need to stay for a long period.

Cheers.

Thank You so much Cristiano for the offer early days yet

I've decided on a course of action and thank you all so much for your support.

:thum bsup: to all of you

[norm]

Hi Trevor,

Best of luck to you and your wife, whatever decision you decide upon.

Going back to your original question, if there is even just the smallest chance of it improving her quality of life, go for it.

Cheers Mate.

Norm

[supernova1965 (Warren)]

Hi Trevor

Both you and your wife keep your chins up My wife has just been told she is officially cured of breast cancer after 5 years of clear tests. I and my wife wish you both all the best and look forward to updates.

[jjjnettie (Jeanette)]

That's great news Warren.
Congratulations to both of you.
Reckon it's been a hell of a journey for both of you.

[Jen]

Originally Posted by supernova1965

Hi Trevor

Both you and your wife keep your chins up My wife has just been told she is officially cured of breast cancer after 5 years of clear tests. I and my wife wish you both all the best and look forward to updates.

great stuff Warren