My 2c worth;
It could well be that the biggest silent contributor to the apparent global warming effect & ozone depletion is the degradation of the geomagnetic field that surrounds the earth. The earth's core (which acts a like a dynamo & generates this field) has slowed down quite significantly over the last few hundred years, and so the earth's field is weakening. This is usually a precursor to a geomagnetic reversal, where the polarity of the earth's field spontaneously reverses itself.
When I say 'spontaneously' I don't mean instantaneously. It could occur over decades, with years of instability before the poles realign & gradually the field stabilises & strengthens again. Apparently this has ocurred many times throughout the earth's history and is evidenced by geological studies. We are currently very much overdue for one.
Of course, as the earth's field weakens, more harmful rays from the sun can penetrate the atmosphere leading to higher incidence of cancers, changes in weather patterns, warming etc. Might also explain all those unusual whale beachings...
So I think we need to keep an open mind about it - although I very much believe that pollution, defoliation etc. significantly contribute to the problem I also believe that mother nature's engine room might also be a big factor....
Of course it might be that the earths core is slowing down for some other reason, but I'd rather not think about that. If it just kept slowing down i.e. not just a reversal, then we'll end up with no ionosphere & the solar winds can happily blow away our unprotected atmosphere, instead of deflecting around it as currently happens. We'd end up like Mars, so there wouldn't be much point in going there anymore hehe....