how about going cat 5e running all that over gigabit i couldn't see lag being an huge issue as the through put is much higher then usb2 i've run full hd 1080p blu rays running from my NAS to the living room over gigabit with 0 stutter. As far as the back and forth "transaction" type of data that would be occuring it should be fine i've also run large busy databases between 2 servers running gigabit with no issues.
Sorry for all the technical jargon,
from my testing with wireless n at that distance you will get 10-20ms latency but this may blow out once you start doing alot of data. then there is the drop outs which always occur