Many thanks to you all for your very nice comments!
Some answers...
Octane: Sorry but I have absolutely no experience with DSLRs, so can't say what the relationship is between a DSLR ISO setting and an OSC camera. If Gain is similar, I set mine to 50.
Louie is still around though very busy I think these days.
Hagar: I focus by the numbers. Usually with a Robofocus, but because the FS-60 wasn't mine and I only had it for a little while, I didn't get to mount an RF motor on it, so had to focus manually. But still by the numbers.
I do a rough focus in highly binned mode (4x4 with the QHY8), using very fast exposures, say 1 second and turn the focus knob slowly, just watching the stars in the resulting image on-screen. When it's close to being focused, I'll sub-frame the brightest star into a very small frame, switch to 1x1 binning (unbinned) and take as fast images as the possible, 1 second or faster, then tweak the focus knob while watching the numbers on screen until the focus sharpeness is maxed (in CCDSoft) or the FWHM is minimised (in Maxim DL). This usually gets it very accurate.
Of course I went to bed after it started taking images (and checking the cloud patterns), so from then it was up to the little scope to not shift focus for the rest of the night, which it didn't, to its credit!
Many thanks again for all your gratious comments