Collimation is where you line up the mirrors and the focuser in the telescope to provide the best possible image. If collimation is off it prevents you from reaching a sharp focus. If you've never looked at it it will almost certainly be off.
Procedures will be described in the manuals that came with the telescope. I'd ignore these. There is a great video on Newtonian collimation here:
http://www.andysshotglass.com/Collimating.html
As your telescope has a built-in barlow/corrector at the end of the focuser tube you won't be able to use a laser collimator. I've used a home made (out of an old 35mm film canister) collimation cap for a 4 1/2" reflector much like yours with much success in the past. You just need something that fits in your focuser with a hole in the middle so your eye is centred in the focuser when you collimate.
Collimation is easy after you've done it a few times. It is a critcal skill to learn. Collimation is essential for viewing detail in nebulas and on planets.
There are many threads on IceInSpace discussing Newtonian collimation.
Have fun,
Doug