Welcome Sean and great first image there.
Settings will really depend on what you are taking a shot of. The moon is a great object to get a handle on, especially shooting the way you are through the eyepiece. M45 will require either a higher ISO or longer exposure to gather enough light.
As for some starting settings ... put everything on manual including focus. Open up the aperture (the lower the 'f' number the more light you are letting in).
Then you need to balance the ISO and shutter as they work in concert together. Higher ISO means the camera is more sensitive to the light so better in darker situations. Problem is that it increases the "noise" you also capture. If you are holding the camera by hand, then you want a shorter exposure to remove the wobble. This means you may need a higher ISO to compensate.
Poita's idea is a great one. The quicker you can get your hands off the camera the better. You'll be able to take longer exposures with less movement. Just remember to set the camera with a 2 or 3 second delay. This way, you hit the button and the whole set-up has a few seconds to stop wobbling.
There have been some fantastic shots taken through a Dob so keep at it!
Cheers,
Af.
