If you take images on different nights of different exposure lengths and different image sizes and different rotations and from different cameras and different scopes and different everything else you can stack them all together in a great program called
Registar
Registar is a powerful tool for stacking images of the same object you have taken over many years from many sorts of cameras and scopes.
I tried it with about 10 of my M42 images taken over the years. They were all different scales, orientations and FOV's, and it stacked them all into one really nice image