According to this page:
http://indilib.org/about/platforms.html Mac OS is supported, so you could give it a try.
I'd check the devices page (
http://indilib.org/devices.html) to ensure your gear is supported.
There are forums there as well to get help if you need.
I've been trialing this stuff under Linux and I think it has great potential. Eventually I hope to move away from Windows completely and just use a Linux setup based on kstars, etc.