If you are using the Sky6, regardless of which options you select it blocks syncs (mostly likely to protect any underlying Tpoint model).
http://sourceforge.net/p/astrotortil...read/b5546e48/
Secondly Tpoint only allows slews to an incorrectly object if you can do a sync first; there is no option to re-slew to target once it has calculated the pointing offset without issuing a sync first. The authors of AT say this option is a bit complex and "may" be available next year.
Finally if you know what you imaging scale is - speed thing up by 1) always having about 20-50 bright enough stars in the imaging, 2) setting tight limits around your imaging scale - say < +/- 5% of your real scale and selecting it to search no farther than +/- 20 degrees from reported RA / DEC.
Lastly putting the image database on a SSD seems to help alot!