3 Sep 2024 In a press release today researchers at the University of Texas in
Austin say they have discovered an antibody able to neutralize all known
variants of SARS-CoV-2, the virus that causes COVID-19, as well as distantly
related SARS-like coronaviruses that infect other animals.
Quote:
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Originally Posted by University of Texas
"The discovery of SC27, and other antibodies like it in the future, will help us better protect the population against current and future COVID variants," said Jason Lavinder, a research assistant professor in the Cockrell School of Engineering's McKetta Department of Chemical Engineering and one of the leaders of the new research, which was recently published in Cell Reports Medicine.
During the more than four years since the discovery of COVID-19, the virus that causes it has rapidly evolved. Each new variant has displayed different characteristics, many of which made them more resistant to vaccines and other treatments.
Protective antibodies bind to a part of the virus called the spike protein that acts as an anchor point for the virus to attach to and infect the cells in the body. By blocking the spike protein, the antibodies prevent this interaction and, therefore, also prevent infection.
SC27 recognized the different characteristics of the spike proteins in the many COVID variants. Fellow UT researchers, who were the first to decode the structure of the original spike protein and paved the way for vaccines and other treatments, verified SC27's capabilities.
The technology used to isolate the antibody, termed Ig-Seq, gives researchers a closer look at the antibody response to infection and vaccination using a combination of single-cell DNA sequencing and proteomics.
"One goal of this research, and vaccinology in general, is to work toward a universal vaccine that can generate antibodies and create an immune response with broad protection to a rapidly mutating virus," said Will Voss, a recent Ph.D. graduate in cell and molecular biology in UT's College of Natural Sciences, who co-led the study.
In addition to the discovery of this antibody, the research found that hybrid immunity—a combination of both infection and vaccination—offers increased antibody-based protection against future exposure compared with infection or vaccination alone.
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Story here :-
https://medicalxpress.com/news/2024-...-variants.html
Newly discovered antibody protects against all COVID-19 variants
I think back about the development of 
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