Quorum Sensing

[xelasnave]

Sorry I cant give you a link (that is another story) but I find this perhaps the most exciting news out there.

Google Quorum sensing and at least watch a short youtube video to get the idea.

It explains how bacterium communicate ( they assess their numbers before they attack in effect) and when our science figures out how to use this information the need for anti biotics will be gone...my side advice is find out the companies working to bring this into the real world and buy stock and thank me for your billions at some point in the future...imagine shares in a company that replaces anti biotics...

Very interesting information and I now wonder if a similar mechanism exists with virus ..which is reasonable to assume as a possibility for thought through reasons...and many ( probably all) cancers are caused by virus ....well if their approach is similar to bacteria then finding a way to stop their communication ( assuming such exists) would be a sure way to manage all cancers...
Just a thought...
Alex

[iborg (Philip)]

Hi Alex


Quorum sensing has been known about for quite a long time.



Bacteria of different strains and species appear to be able to use it, when working together to construct biofilms.


It is truly amazing how a few simple 'rules' can produce complex behaviour.


Philip

[xelasnave]

Yes Phillip

Discovery. Quorum sensing was first reported in 1970, by Kenneth Nealson, Terry Platt, and J. Woodland Hastings, who observed what they described as a conditioning of the medium in which they had grown the bioluminescent marine bacterium Aliivibrio fischeri.
https://en.m.wikipedia.org › wiki
Quorum sensing - Wikipedia

It surprises me I only found out about it six months ago...

Alex

[iborg (Philip)]

Hi Alex


Where I worked used to get New Scientist, and they had many years of back issues, so my head wound up full of all sorts of bits of information like this.


Of course, I could never remember the details properly.


Philip

[xelasnave]

The key to knowledge is to remember a little something and where to look...think of a lawyers office

Although my old master solicitor seemed to have remembered it all..you could ask him to help with a problem and he would suggest the book, the page number, the paragraph and the section therein.... All at 89 years old..an inspiration and a wonderful mentor...me very lucky...
Alex

[Nikolas (Nik)]

"Biofilm production comes to a simultaneous halt across all V. cholerae bacteria, and a new sequence of quorum sensing moves V. cholerae through its infectious process. With this knowledge, researchers are now exploring V. cholerae’s quorum-sensing process as a therapeutic target. For instance, one exciting study demonstrated that overloading V. cholerae with its autoinducer can halt the process of biofilm formation completely, and potentially delay the infectious process enough for our immune systems to catch up. Disrupting the bacterial communication structure is an exciting innovation and practical response to the sharp rise of antibiotic resistance across bacterial species."




Interesting read they are starting to develop strategies, maybe Alex is onto something here

[iborg (Philip)]

Hi Nikolas


For cholera, it may be better to 'set a thief to catch a thief', so to speak.


Bacteriophage may be a better option than drugs, even if only because they will also adapt to the changes in cholera as they occur.



https://theconversation.com/phage-th...acteria-117058


Before antibiotics, bacteriophagehad started to be used seriously in a few places, and I think work continued on them for quite a while in the USSR.


Philip