QHY600M 3.76 microns binned 2x2 is hardware binned not software binned. Gives 7.52 micron pixels at 90% QE.
It works just fine on my CDK17:
https://pbase.com/gregbradley/image/171682364
The other advantage of 2x2 is 30mb files instead of 120mb for 1x1 which are slow to process.
Greg.