Have a read of
this thread- it's filled with loads of helpful advice in helping to find galaxies. Posts #36 % give a fantastic star hop tip to finding M104 (The Sombrero galaxy).
Remember... galaxies are best viewed when the moon isn't around and the object is nice and high in the sky. Avoid Zenith if you have a dob- it can be difficult.
I have a great little app. on my android phone that tells me when the moon is going to buzz off, take a look
here.
Even when the moon is in its waning and waxing crescent phases, there are times when it'll rise later in the night allowing you a few hours to observe those galaxies without it.
