I always take my flats, dark flats and bias frames as I'm tidying up for the night. Flats and bias frames taken under the same conditions as the lights are very important for me to do. Darks are from a library that are at most a few months old but can be done at any time.
Check what average ADU your flats are at. I find between 1/3 to 1/2 full well depth in the histogram is best. I now use Sequence Generator pro which calibrates the flats to give a user designated time of exposure with my light box to give an exact ADU for every filter. Solved all my flats problem in one step.
Allan
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