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It certainly cleaned up the noise well. Its interesting most of the noise appears to be luminance noise rather than the usual chroma noise (smarties). That's half the battle already.
I find some noise reduction routines take out faint stars (Nikon View NX2 but their astro noise reduction isn't bad). Lightroom 4.3 is good for noise reduction as well, particularly chroma noise. I use Noise Ninja (but not so much on DSLR shots as it attacks the stars too much) but I think your Topaz is doing a better job there. Its a touchy area of processing as too much and it makes the image take on a plastic feel as it is basically blurring. Too little and it looks grainy. Selective noise reduction is the usual algorithim that works best where it is applied mostly to dim areas and not bright areas.
By the way have you experimented with what point you do noise reduction? With DSLRs I do it with RAW conversion and perhaps late in the processing chain if it needs more and with CCD it is done early (deconvolution usually on the combined masters of each LRGB - usually just on luminance but sometimes on one or all of the RGB to get star sizes to match).
I'll download a trial of it and check it out more.
Greg.
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