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I don't have a "back to back" comparison with the same cameras -mono-OSC...
But I do know the sensitivity of a OSC due to the Bayer matrix, compared with a mono is around 70% (at best)
We're not comparing resolution...but general QE....binning is also an issue when it comes to guiding...not all (any???) OSC cameras can give say 2 x 2 binning....
I used the original QHY5 for a while, but ended up going to the Lodestar for guiding on fainter stars for spectroscopy.
Hope this helps...
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