Hi Pete,
I replaced the focuser on my Bintel (GSO) 8"F4 with a Moonlite.
No issues about hole alignment. You buy the mounting plate and focuser from Moonlite for your scope diameter.
The mounting plate comes pre-drilled and tapped with about 24 holes, if remember correctly, to suit most mounting hole patterns. You just screw into it from inside your tube.
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