In addition to Chris' advice above, you might look into
http://hulse.id.au/eqmac/ for scope control. Haven't used it personally, but it appears promising.
Pretty sure Astroplanner can control LX200 mounts native in Mac.
Personally, I use a MacBook Pro, but run all image capture and guiding software in a WinXP virtual machine using VMWare Fusion. The availability of astro software Win-based is far greater than Mac. I use PixInsight in OSX for processing.