You would use a separate guide telescope piggybacked on your main scope, or an off-axis guider, which attaches to the focusser of your main scope and has a small prism which comes out at a right angle to the optical axis.
With either method, you use an illuminated reticle eyepiece, place your guide star on the crosshair and use your R.A. and Dec controls to keep the guide star centred on the crosshair
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