I have used 2 scopes as guide scopes both with the same side by side mount and the same guide camera- a QHY guider.
The first was a 120mm skywatcher acro with a focal length of 600mm. The second is my 127mm APO refractor with a fl of 950mm.
The 127mm is heavier but both were connected the same way. I can always get a guide star with a 0.5sec exposure with either scope. I found though that the longer FL APO refractor does give me better guiding.
Differential flexure was similar for both.
Whilst the guider can do sub pixel guiding it has less problems at the longer FL.
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