Yes, clouds above a dark site cause very high readings.
Away from lights in the mountains, deserts, mid ocean, etc, during new moon and under clear skies will result in readings no more than the very low 22 mark, according to Anthony Tekatch and experience.
Bright stars and the MW passing through the FoV of the SQM-L(E/U) models will cause lower readings, even at truly dark sites during new moon, so best to aim at something like the SCP for consistent numbers.
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