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Peter,
Just a few other potential problems that I can brainstorm which may be worth investigating if you have no further luck:
* Which COM port numbers are the Keyspan adapters mapped to? The software may be expecting it to be a different number to what was auto assigned by Windows.
* Check whether the port settings (rate, parity, handshaking, stop/start bits, etc) are configured the same at the operating system level - in Device Manager. Software can (and should) override the OS defaults, but sometimes they don't. There are also other advanced settings (FIFO buffer length, send/receive latency, etc) that sometimes causes grief.
* Check whether the cable that works has any other pins shorted. Some devices will expect that RTS/CTS are active high (and won't work without them being set). EQDIRECT cables for EQ6 mounts need an extra ground and two supply pins - on top of the standard 3 pins.
Good luck!
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