I doubt that you have ruined it but something has slipped while you were replacing the screws possibly.
It has a center pivot point ball under the secondary that may no longer be in the middle.
Loosening the screws could cause this to drop to one side if you did it with the scope on its side ( the safe way to do it just in case anything falls off inside ).
All three screws should be kept firm to stop this from happening.
It sound like you may have loosened thing too much.
Safest thing to do now is to remove the corrector plate and disassemble the adjuster and have a good look to make sure all is well and in position.
Don't be afraid to do this just take your time and as stated make sure you don't turn anything from its original location.
If you don't fancy doing it yourself by all means find someone you know has done this before to do it for you.
If you do it yourself just remember to make a small mark at the edge of the corrector plate and the tube ring so you know where to put it back, use a paint pen or similar and put a small dot on the glass edge and the ring.
With the corrector out support it with the secondary face down using soft cloth eg T shirt material and a couple of layers of tissues under the secondary mirror to protect it when the screws come out and then remove the three screws to check the position of the pivot ball and wave/cup washers. The wave washers are there to give some spring in the adjustment, they are cup shaped and should not all be facing the same way, the cups should face each other to give the flex needed.
You will see why the screws should never be loosened too much when doing this and when sure all is ok reassemble it all making sure there are no finger marks on the inside and the corrector goes back in the same place it came from and not turned at all.
Re-do the collimation check but do not loosen any of the screws more than a half turn at a time and tighten the opposite side screws by the same amount to keep all in place and prevent the parts from slipping out of place inside and then try your focus again.
Hope this helps.
PS if you want to try this yourself I do have some pictures somewhere of what it looks like inside, let me know and I'll post them for you.
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