I suggest a shell mechanism seems important but may not be exclusive of other mechanisms but it would seem the first step must be the creation of some type of seperation from the outside... a drop of water would seem perfect.
This thread causes one to embrace just how very complex something, we take to be simple, can be...a mere cell (modern one

) yet so much to it...and applying russian doll imagination down to the atoms and their parts and how those parts can be described as a point movement via string theory you need a good deal of imagination just for a very simple overview.
The chemistry (my old love) appeals to me.
alex.