|
They left out the stump jump plough!
Relenza was invented by the BRI and CSIRO with Dr Peter Colman as research leader and Dr. Jose Varghese by elucidating the molecular structure of neuraminidase an enzyme that the flu virus uses to escape infected cells. Most of the technical experimental work was done by me. The chemical synthesis of various compounds were done at the Pharmacy College under our direction.
Tamiflu was a 'me too' drug that just evaded our patents.
In the early nineties Jose predicted that tamiflu would produce viable mutants of flu in a Nature paper. Relenza never would as it's binding constant was almost identical with the target molecule of neuraminidase. This has come to pass as predicted by Jose.
The Wright brothers got the information for lateral stabilty from Hargraves who had working manned hang gliders in the 1890's.
We punch way above our weight as far as scientific publications go as a proportion of our population.
Bert
|