I used to run SETI a decade ago, and was heavily into distributed computing looking at protein folding (which unlike SETI did have some actual positive results) for many years, but rising electricity costs stopped my activities. I worked out that my current overclocked quad core CPU alone (disregarding rest of the system power) could use about a dollars worth of electricity per day when under 24/7 100% load, and I wasn't willing to continue shelling out over 300 bucks worth of electricity per year to other peoples projects anymore.
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