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AN OIII filter washes everything to green, it kind of kills any natural colour that's there.
I have an 8" dob at in a 25mm ep (x48) I can fit a quarter of the Rosette in. That should give you some idea of how big it is. With a 10" you'd probably be looking at a slightly smaller area of sky, depending on the eyepiece being used, but I wouldn't expect to see it all in one go. (Not unless you've got a scope with a very short focal length and hence a very wide field of view!)
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