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Deep Sky Stacker and IRIS are very popular free programs. IRIS looks hard to use, but there are manuals "step-by-step" which are easy to follow. RegiStax is institution in the processing of Moon and planetary images.
PixInsight, MaximDL, Nebuolosity, Image Plus are popular paid packages. Every one of them has unique features.
And in the end you can stack images manually in PhotoShop or Gimp (free one), but it is time consuming and you will not be able to use the astro dedicated features and algorithms of the specialized softs.
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