I don't know it you can get one for your lappie, but I have a SATA caddy to replace the DVD in my Thinkpad with a 500GB HDD in it. It's about as fast as the boot HDD in the box.
There's no reason you couldn't use a firewire HDD. You would need to check on the wiring (there are at least 2 different plugs) and whether you need external power.
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