Hi Coen, the Homunculus itself is very bright and quite pronounced as two lobes protruding in opposite direction from Eta and you should be able to spot 'something' around Eta in pretty much the smallest scope. However to see clear details in the lobes a large scope is preferable, I would guess 200mm+.
16 arcseconds sounds about right. I took an image of it last year with quite a lot of detail, see thread here:
http://www.iceinspace.com.au/forum/s...ad.php?t=56087
I'm using a 250mm Newtonian.