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Gday JJJJ
My vote is thermal noise too. Can Isggest a solution if you dont want to delete the data. Assume you're using PS. It wont be as good as starting weith no noise but it might give you something.
Duplicate image -> on new image run whatever noise reduction filter you like (Carbonis, noise ninja etc etc) or use the Filter -> Dust and Scratches in PS and set it at about 2 pixels (it is pretty harsh so play around with settings (or even Median filter it I havent tried that) - note that now you have lost a fair bit of detail but the main neb in your image doesnt look too bad so use that but again.
On the noise filtered image select all (Ctrl A) and copy (Ctrl C) then set focus to the original noisy image and paste the noise filtered image in as a new layer - you will see the filtered image (make sure you do - you want that to have focus) then select Layer -> Layer Mask -> Hide All and you should now only see the noisy image. Now select the paintbrush and select a suitable brush size (top left) and paint in where the noisiest stuff is. You are painting aaway the noisy image and letting the filtered image at the back come through. Limit painting to background otherwise you lose detail. Yoou could change the opacity of the brush near the edge when you want stop painting - (beside the brush size) by palying around you might be able to blend the two pretty well (Again alternatively runa Gaussian Blur of the Layer mask to assist in blending) . When happy select Layer -> Flatten Image.
I did a strip on the right hand side of your image (still looks pretty crappy but)to show what I mean.
Hope this helps now or in the future (with maybe a bit less noise). Saves running a really strong noise filter on your whole image and losing detail.
Mark
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