well generally you can enlarge the image and work with it at a larger size, ever noticed when you shrink a image down it always looks nice and sharp. so if you go to Image-->Image size and then increase it by say 5% at a time you will end up enlarging the image significantly working at this resolution will allow you to shrink it back to a A3 / A2 size. my images are generally shrunk 20-30% to fit onto a A3 print
If you want to try out deconvolution you can try it out with ccd stack, it has quite a good deconvolution program in it.
do a heavy deconvolution ~150 and a lighter one ~50 iterations, then selectively mask them in. youll have some really good results utilizing this method.
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