It's not going to kill off 100% of all the animals, so those mammoths descended from remnant populations after the impact is no big deal. But it would've killed off the majority of most of the animals. One thing it did do and that's wiped out the Clovis Point people. After the initial phase of the Younger Dryas, they disappeared from the scene...or at least the culture did.
It also ultimately depends on the impact itself. Sometimes these events happen and not much happens. Other times they happen and all hell breaks loose.
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