How about a colour technology behind each pixel using a microscopic prism array so rather than a Bayer matrix - each pixel detects LRGB across four distinct counters. I believe such ICs have already developed and successfully tested?
That and a materials technology that doesn't need very lower temperatures to have low read noise would be great.
An algorithm that intelligently switched each pixels' pixel well from an integer to a float (once the well as an integer would otherwise be swamped) I am sure is on the cards.
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