I think the best space cartoon has the character known as
Marvin The Martian (or Commander X-23) in the 1953 - "
Duck Dodgers in the 24 1/2 Century."
The actual story-line follows Daffy Duck (Duck Dogers) who sets out to find him and a mineral the Earth wants. He follows from Planet A to Planets B, C, D, etc., until he reaches the designated
Planet X. He immediately claims it for Earth, when also Mavin arrives in the ship, the Martian Maggot, who instead claims it also for Mars!!
A interplanetary battle for the planet ensues, which in the end is destroyed, blown to kingdom come... It ends with the statement "
B-B-B...ig Deal" !!
Just Brilliant...
See
http://video.yahoo.com/watch/42704 for a vid of the cartoon...
Are there any others of space cartoons of note????? 
Surrender or be blown into 17,670, 002 microcells!!
...or get me the Illudium PU-36 Explosive Space Modulator !! 