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I've owned both, and did significant observing in my 10" but not so much in the 12" (it's primarily to photograph planets).
The 12" is significantly larger than the 10", so if portability is a major concern, then yes - go the 10".
You *can* put the 12" on an EQ6 (I do), but you'll need a heavy duty dovetail and custom rings. It increases the cost a lot.
There are ready available rings for a 10" newt so the solution is easier and cheaper to mount on an EQ6.
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