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Quantum theory surprisingly helps here, without causality (time flowing in only one direction) it can be shown most models of creating a universe from a big bang + inflation physics leads to a tangled mess (Scientific America July 2008).
Relativity and Newtonian physics really deal with properties of matter and energy within the fabric of normal spacetime - not the meta rules that must be present to shape the underlying properties of spacetime itself (such as its topology and causality).
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