I have the holes but not the grub screws.

This is a new scope.
Am I screwed?
CAN i COLLIMATE WITHOUT THESE?
My other question was,
what happens if the primary mirror isn't centred properly.
Ie if it is 0.1mm or 0.2mm or 0.3mm or 0.4 mm off
Is this error acceptable.
or put another way
What margin or error is there available when marking the primary?