John, a guide scope is a second smallish scope, of about 500mm focal length to which one attaches a web cam or similar type of camera.
This scope usually attaches to the main scope, and as the image is seen through the guide scope with the attached web cam or similar the information needed is transfered to the mount, so that corrections in following the object can be made.
I hope this helps a bit, some others here may be able to explain it better.
Leon
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