When running ImagesPlus with the 350D, I use ICNR and Mirror Lock Up at ISO1600. I just set both of these functions in the camera itself within the custom functions, or I think if you just check the boxes in the 'Bulb Capture' tab in ImagesPlus it will set them in the camera anyway. As the others have mentioned here, have a go with a standard ISO setting and see what you get.
Michael
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