Yes,
A prism splits the light path into two separate eye pieces. I have once tried them with Vixen LVW 22mm eye pieces on a C9.25 - great views of Saturn and Jupiter.
The key advice is 1) its a lot of weight - make sure your gear can handle it - particularly the collars - so they don't slip out! and 2) ensure your OTA has enough focal range to bring everything into focus - which is no problem on a SCT or MAK.
Matt
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