Ian even with plate scales (pixel scales) of 5.9 arcsec/pixel and 3.9 arcsec/pixel, and using an Atlux mount unless your polar alignment is very accurate you will still get Declination drift over time. How quickly your drift will become noticeable depend on the amount of the error in your altitude and azimuth misalignment. This is the value of the autoguider, not only to take care of periodic error but to correct for polar misalignment that would affect declination drift. Its a long call but I would say that any focal length over about 100-135mm would benefit from autoguiding, as a general rule.
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