About 10 minutes.
Walk out, open observatory, remove dust covers and lens caps, power on mount - recall last pointing settings, slew to a reference star clsoe to where I want to start imaging and adjust calibration stars if pointing is more that 2 arc minutes off, boot PC.
That takes about 5-7 minutes.
Start PHD, do a calibration run - say 3 minutes. Capture first image - say 2-3 minutes, check all is okay, start VNC server and script with DSLR shutter a imaging run for one target - e.g. 10 * 2 - 20 minute shots of target - walk away and close lab.
Start VNC client indoors - play with kids - check everything is okay every 1/2 hour or so. Once family goes to bed - either stack and process some images on PC inside whilst I select next target - or watch tv or DVDs while the gear does the work and save image processing for another day.
At 2am - take some darks, re-set gear, power down, cover everything up, send all images to network storage and lock up - go to bed!