I have a 10" and it's easy enough to shift around with a hand-trolley. The OTA is over 20kg and the base is fairly heavy plus the assembled scope is extremely awkward, so It is a BIG strain on the back to carry it by hand more than a few yards. I pretty much stick to the back yard, but it would go in an average car easily enough (without many passengers!).
The 8" is definitely more portable, but it's light gathering power is quite a bit less, though you can say the same about the difference between the 10" and 12".
One other thing to consider is the f-ratio. I assume the 8" is higher than the 10". I do find that with some eyepieces (hey, I can't afford televue!) the effect of coma means the outer area of the eyepiece can be quite stretched.
A couple of other bits of advice, get one with the 10:1 fine focuser and right angle finder, they make a big difference. Also splash out on a Telrad ($79 from Bintel). The Telrad is easier to fit on the dobs (unless you don't mind removing the finder) than similar red dot finders and makes pointing the scope a doddle compared to crouching down and trying to do it by eye..
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