"Save for web" is what I use too.
Roger I notice that quality difference too, but I think it's more a case of people not utilising the tools to their full potential, or using the wrong tools.
FOr example, i've seen some inexperienced in image editing saving them as 2000px wide jpegs, and so the compression is absolutely horrible in order to get it under 150k.
I guess for us planetary imagers we're quite lucky. I've been able to save quite big planetary image composites and 40% save-to-web compression and the compression artifacts are still not really noticeable unless you *really* look for them.
I've noticed for deep-space images it's much tougher to get good compression without artifacts.
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