An interesting question. It appears that the ASCOM drivers should provide the flexibility to do what you are suggesting. Here is a link that might help you, with relevant text pasted below.
"(Note that I have three programs that want to communicate with the telescope mount: Cartes du Ciel, AstroArt and GuideDog. But only one program can control the computer’s serial port at a time. So how can this work? Via ASCOM. ASCOM is a free software suite that makes it easier for programmers to write programs to control telescopes – that’s its primary purpose. But it also provides a software “hub” that allows many programs to talk to the hub while the hub has exclusive control over the telescope’s serial port communication. My three programs connect to the ASCOM hub and the hub connects to the telescope mount.)"
http://www.bpccs.com/lcas/Articles/i...my_part_II.htm