Quote:
Originally Posted by bluescope
Canon L series lenses are simply the best in their class hence the high price tag but they are well worth the expense if you want superb optics ...

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I wouldn't say there's a difference besides that Nikon only has VR in the 300mm and not the 400mm, Canon has IS in the 300-600 range. NASA uses Nikon Telephoto lenses in space with Kodak-Nikon bodies.